Rifabutin could be securely utilised with regular doses of raltegravir and dolutegravir but is contraindicated with elvitegravir/cobicistat. Using bictegravir with possibly rifampin or rifabutin is contraindicated. [87]Croxford S, Kitching A, Desai S, et al. Mortality and causes of Dying in men and women diagnosed with HIV inside the era of hugel